But he took off in the final 10 overs as he cracked 52 runs off his last 21 balls to cruise to his maiden 150 off 138 deliveries.
Padikkal now has 301 runs from three matches, averaging 100.33 with scores of 52 and 97 in the first two matches.
In reply, Odisha were bowled out for 228 in 44 overs with Prasidh Krishna and Sheyas Gopal grabbing three wickets each to hand Karnataka their second win from three matches to move to second spot in the standings.
In another Group E match, Kerala defeated Railways by seven runs in a high-scoring thriller at the Just Cricket Academy to register their third win on the trot and consolidate their position atop the table.
Veteran opener Robin Uthappa (100 from 104 balls; 8x4s, 5x6s) cracked his second century from three matches in company of fellow opener Vishnu Vinod (107 from 107b; 5x4s, 4x6s) before Sanju Samson took charge with an explosive 61 to power Kerala to a massive 351 for 6.
Samson, who was appointed Rajasthan Royals skipper after they parted ways with Steve Smith, clobbered six fours and four sixes in his 29-ball knock, while Vathsal Govind remained unbeaten on a 34-ball 46 (2x4s, 3x6s).
Half-centuries from Mrunal Devdhar, Arindam Ghosh, Saurabh Singh and Harsh Tyagi meant the match went down to the wire.
But medium pacer MD Nidheesh (3/83) took two wickets — Amit Mishra and Tyagi — in successive balls in the last over to take Kerala over the line in a dramatic finish.
Karnataka 329/5 in 50 overs (Devdutt Padikkal 152, Ravikumar Samarth 60, Krishnamurthy Siddharth 41, Abhimanyu Mithun 40 not out) beat Odisha 228 in 44 overs (Subhranshu Senapati 78, Ankit Yadav 56; Prasidh Krishna 3/46, Shreyas Gopal 3/47) by 101 runs.
|Gaurav Choudhary||ct B R Sharath b M Prasidh||20||17||117.65||3||0|
|Sandeep Pattanaik||Run Out Suchith J||28||31||90.32||6||0|
|Subhransu Senapati||Run Out Samarth R||78||92||84.78||3||2|
|Shantanu Mishra C||ct & b Shreyas Gopal||11||16||68.75||1||0|
|Abhishek Yadav||lbw Shreyas Gopal||6||13||46.15||0||0|
|Rajesh Dhuper W||ct B R Sharath b Suchith J||0||3||0||0||0|
|Ankit Yadav||ct V Vyshak b Shreyas Gopal||56||63||88.89||6||1|
|Saurabh Kanojia||ct Suchith J b M Prasidh||3||15||20.00||0||0|
|Suryakant Pradhan||ct Shreyas Gopal b M Prasidh||8||5||160.00||0||1|
|Rajesh Mohanty||ct Rakshith S (Sub) b V Vyshak||1||7||14.29||0||0|
|Harshit Rathod||Not Out||1||3||33.33||0||0|
|EXTRAS||(nb 1, w 4, b 0, lb 11, pen 0)||16|
|TOTAL||(All out; 44 overs)||228|
- 1-55 (Gaurav Choudhary, 7.4 ov) ,
- 2-62 (Sandeep Pattanaik, 9.1 ov) ,
- 3-81 (Shantanu Mishra, 14.6 ov) ,
- 4-93 (Abhishek Yadav, 18.4 ov) ,
- 5-98 (Rajesh Dhuper, 19.6 ov) ,
- 6-204 (Ankit Yadav, 38.1 ov) ,
- 7-217 (Saurabh Kanojia, 41.3 ov) ,
- 8-217 (Subhransu Senapati, 41.4 ov) ,
- 9-220 (Rajesh Mohanty, 42.6 ov) ,
- 10-228 (Suryakant Pradhan, 43.6 ov)
|Samarth R C||st Rajesh Dhuper b Shantanu Mishra||60||83||72.29||4||0|
|Devdutt Padikkal||ct Rajesh Dhuper b Suryakant Pradhan||152||140||108.57||14||5|
|Siddharth K V||ct Rajesh Mohanty b Harshit Rathod||41||32||128.13||5||1|
|Karun Nair||ct Rajesh Mohanty b Harshit Rathod||25||22||113.64||3||0|
|Aniruddha||b Suryakant Pradhan||1||2||50.00||0||0|
|Mithun A||Not Out||40||17||235.29||0||5|
|Suchith J||Not Out||5||6||83.33||0||0|
|EXTRAS||(nb 2, w 2, b 1, lb 0, pen 0)||5|
|TOTAL||(5 wickets; 50 overs)||329|
|Shantanu Mishra C||7||0||39||1||5.57|
- 1-140 (Samarth R, 27.2 ov) ,
- 2-205 (Siddharth K V, 38.5 ov) ,
- 3-280 (Devdutt Padikkal, 45.2 ov) ,
- 4-283 (Aniruddha, 45.6 ov) ,
- 5-283 (Karun Nair, 46.1 ov)
What Time KAR vs ODS – Vijay Hazare Trophy 2021 Will begin?
Vijay Hazare Trophy 2021 Will begin at 9:00 AM IST
What are the venues for VHT 2021?
Vijay Hazare Trophy 2021 will be played at Surat, Indore, Bangalore,
How do I watch live streaming of KAR vs ODS – VHT 2021?
The live streaming of the Vijay Hazare Trophy 2021 will be available on Star Sports. You can also catch the live updates on insidesport.co